Vaginal applicators play a crucial role in women’s health, making it easier to administer various treatments and maintain optimal vaginal health. In this comprehensive guide, we’ll discuss the purpose of vaginal applicators, how to use and clean them, and share expert advice. What is a Vaginal Applicator? Less serious, but common side effects include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps/bloating, nausea and vomiting, hair loss, fluid retention, vaginal yeast infection, reactions from Premarin Vaginal Cream such as vaginal burning, irritation, and itching. INDICATION Apply regularly to achieve the best result. This could start with daily application(s), and then after about a week changes to every third day. YES VM is safe to use every day, or whenever is needed for soothing and relief. Rusi Health, based in Yorkshire, is a family business that promotes certified organic, plant-based, natural feminine products that enhance a woman’s wellbeing and intimate health. Our goal is to ensure women are aware of the health risks that come with certain types of feminine products made with synthetic chemical ingredients. We offer safe, healthy alternative feminine products. Estriol, a weak oestrogen, is a natural metabolite of estradiol, the predominant oestrogen. Estriol exerts estrogenicity by binding to oestrogen receptors, present in the female genital tract. Estriol, oral or vaginal, similar to estradiol, corrects lowered proliferation and abnormal physiology in the atrophic vaginal epithelium seen in oestrogen deficient states, such as after natural or surgical menopause. In contrast, the histology of the endometrium after using Gynest Cream rarely shows minor signs of proliferation in previously atrophic endometria.

Long-term use of oestrogen-only and combined oestrogen-progestogen HRT has been associated with a slightly increased risk of ovarian cancer. In the Million Women Study 5 years of HRT resulted in 1 extra case per 2500 users. To apply the cream, lie down, put the end of the applicator deep into your vagina and slowly push the plunger all the way in. Ritonavir and nelfinavir, although known as strong inhibitors, by contrast exhibit inducing properties when used concomitantly with steroid hormones. Herbal preparations containing St. John's Wort ( Hypericum perforatum) may induce the metabolism of oestrogens. With intravaginal administration, the first-pass effect in the liver is avoided and thus, estriol given intravaginally might be less affected by enzyme inducers than oral hormones. Some people may avoid seeking treatment for this condition, as they feel uncomfortable discussing it with their partner and doctor. What other options do I have if OTC moisturizers aren’t workingGenerally recognised risk factors for VTE include a personal history or family history, severe obesity (BMI > 30 kg/m 2) and systemic lupus erythematosus (SLE). There is no consensus about the possible role of varicose veins in VTE.

Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke. HRT use does not improve cognitive function. There is some evidence of increased risk of probable dementia in women who start using continuous combined or estrogen-only HRT after the age of 65.

Shortage of oestrogens may cause the vaginal wall to become thin and dry. So sexual intercourse may become painful and you may get vaginal infections. These problems can be relieved by using medicines like Estriol 1mg/g cream which contain oestrogen. It may take several days or weeks before you notice an improvement. Estriol may possibly increase the pharmacological effects of corticosteroids, succinylcholine, theophyllines and troleandomycin. To further assist you in understanding and using vaginal applicators, we have compiled a list of frequently asked questions: How often should I replace my reusable vaginal applicator? YES VM has been designed to match and restore the pH of vaginal tissues, and help maintain vaginal health Insert the loaded applicator into the vagina and empty it (press the plunger part into the barrel part)

It is uncertain whether there is a similar risk with this medicine if used for repeated or long term (more than one year) treatments. However, this medicine has been shown to have very low absorption into the blood, therefore the addition of a progestagen is not necessary. One applicator-dose (applicator filled to the red mark) is 0.5g Estriol 1mg/g cream containing 0.5 mg estriol. Estrogens should be used at the lowest dose possible, only for as long as needed. You and your healthcare provider should talk regularly about whether you still need treatment. This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Where should I keep my medication? For treating a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis) in postmenopausal women, and inflammation of the urethra (urethritis) in postmenopausal women:HRT is associated with a 1.3-3-fold increased relative risk of developing venous thromboembolism (VTE), i.e. deep vein thrombosis or pulmonary embolism. The occurrence of such an event is more likely in the first year of using HRT (see section 4.4). Results of the WHI studies are presented: Due to the vaginal administration and minimal systemic absorption, it is unlikely that any clinically relevant drug interactions will occur with Estriol 1mg/g cream. However interactions with other locally applied vaginal treatments should be considered. HRT, especially oestrogen-progestogen combined treatment, increases the density of mammographic images which may adversely affect the radiological detection of breast cancer.