Bhopal RS. The inter-relationship of folk, traditional and Western medicine within an Asian community in Britain. Soc Sci Med. 1986;22(1):99–105. Several strategies have attempted to reduce inappropriate use of antibiotics. “Delayed” prescriptions (which patients are advised to take only if they are not starting to improve after a certain time) reduce consumption of antibiotics while maintaining patient satisfaction [ 9], but many patients would still like to take medication to relieve their symptoms because a moderately bad cough is known to persist for around three weeks on average [ 6, 10]. Commonly recommended treatments like steam and ibuprofen make little or no difference to symptom severity [ 11]. Other potential symptomatic treatments in adults (the expectorant guaifenesin, mucolytics and antihistamine-decongestant combinations) have not been shown to have consistent benefit in a recently updated Cochrane systematic review [ 7]. Kaloba is a herbal medicinal product made from the pelargonium root (Pelargonii radix) (Capeland geranium) for the symptomatic treatment of acute bronchial infections with cough and mucus production.

In recent years, the inappropriate prescription of antitussive pharmacological treatments in children has decreased; however, paediatricians’ prescriptions currently do not always reflect an accurate treatment of cough [ 3]. According to epidemiological data, cough occurring in children produces more anxiety than in cough occurring in adults, and many people view this symptom as “a disease”. A recent Italian survey confirms this view, suggesting that some inclinations of paediatricians’ therapeutic practice should be modified to achieve better control of cough in children and to reduce its impact [ 3]. Moreover, when attempting to treat cough, children are administered over-the-counter products with little or no scientific evidence of proven efficacy [ 6]. In 2018, the Cochrane Collaboration reviewed six randomized controlled clinical studies that investigated the use of honey to treat acute cough in children. The authors concluded that honey alleviates cough with a greater size effect than diphenhydramine, an antihistamine drug classified as a cough suppressant in the United States, placebo or no treatment and with little or no difference compared to dextromethorphan [ 12]. Kaloba is of pharmaceutical quality and has been manufactured to European Good Manufacturing Practice (GMP) Guidelines

Directions

Although there are no data on cases of overdose, overdose is likely to increase side-effects. Thus, treatment should be symptomatic and as clinically indicated. 5 Pharmacological properties 5.1 Pharmacodynamic properties HATRIC was registered on the ISRCTN registry ( ISRCTN17672884) on 16 August 2018, retrospectively registered. The record can be found at http://www.isrctn.com/ISRCTN17672884. Children were orally treated with KalobaTUSS ® or placebo for 8 days. Children receiving KalobaTUSS ® showed an early and significant reduction in night-time and day-time cough scores measured using a specific scale and a shorter duration of cough than children treated with the placebo. Conclusions Unfortunately, it proved very difficult to interview patients who did not agree to participate in the trial. The two non-participants explained that they were both initially willing to participate, but one was not eligible and the second declined due to potential side effects (headaches), imminent holiday plans and she was not keen to commit to filling in a daily diary. Not required as per article 16 c (1) (a) (iii) of Directive 2001/83/EC as amended. 5.2 Pharmacokinetic properties

Pelargonium sidoides DC (Geraniaceae) root extract, EPs®7630 or “Kaloba®”, is a widely used herbal remedy for respiratory infections, with some evidence of effectiveness for acute bronchitis. However, it is not yet widely recommended by medical professionals in the UK. There is a need to undertake appropriately designed randomised trials to test its use as an alternative to antibiotics. The aim was to assess the feasibility of conducting a double-blind randomised controlled trial of Pelargonium sidoides root extract for treatment of acute bronchitis in UK primary care, investigating intervention compliance, patient preference for dosage form and acceptability of patient diaries. Study design The World Health Organization has identified honey as a possible demulcent treatment for cough [ 7, 8]. Demulcent is a substance that is usually based on polysaccharides, covers the throat and reduces pain when the mucosa is irritated by increasing saliva production to reduce the cough reflex [ 9].

PHARMACIST ONLY MEDICINE

Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity and toxicity to reproduction. 6 Pharmaceutical particulars 6.1 List of excipients One of the most captivating herbal aid of Pelargonium sidoides has been curing tuberculosis, which eventually led to its foundation in the late 1890s in Europe. 6. Used in Ethnoveterinary Applications Matthys H, Kamin W. Positioning of the bronchitis severity score (BSS) for standardised use in clinical studies. CurrMed ResOpin. 2013;29(10):1383–90. If you get any side-effects, talk to your doctor, pharmacist or nurse. This includes any possible side-effects not listed in this leaflet. You can also report side-effects directlyvia the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard. By reporting side-effectsyou can help provide more information on the safety of this medicine.

A. Fever, diarrhoea, restlessness, dark coloured urine, fatigue and stomach disturbances are some common side effects. However, due to insufficient research, some individuals like pregnant mothers, lactating mothers and even children should refrain from its consumption. Q. How can you use geranium oil?If you suffer from an increased tendency to bleeding and/or take anti-coagulating drugs such as warfarin, there is a theoretical risk that taking this product may increase the risk of bleeding.